Periactin is a brand name for the medication cyproheptadine. Here is a briefing about Periactin (cyproheptadine):

Drug Classification

Periactin is a first-generation antihistamine and antiserotonergic medication.


Periactin is primarily used to relieve symptoms associated with allergies, such as hay fever, allergic rhinitis, and allergic conjunctivitis. It can also be prescribed for other conditions, including appetite stimulation, and as a treatment for certain types of headaches, such as migraines.

Mechanism of Action

Periactin works by blocking the effects of histamine, a substance in the body that is released during allergic reactions. It also has antiserotonergic properties, which contribute to its use in treating migraines and appetite stimulation.


Periactin is typically taken orally as directed by a healthcare professional. The dosage and duration of treatment will depend on the specific condition being treated and the individual’s response to the medication.

Precautions and Contraindications

Periactin should be used with caution in individuals with certain medical conditions, such as narrow-angle glaucoma, urinary retention, asthma, or stomach ulcers. It may also interact with other medications, so it is important to inform your healthcare provider about any existing medical conditions or medications you are taking.

Side Effects

Common side effects of Periactin may include drowsiness, dizziness, dry mouth, blurred vision, constipation, and increased appetite. These side effects are usually mild and temporary. However, if you experience severe or persistent side effects, it is important to contact your healthcare provider.

Duration of Treatment

The duration of Periactin treatment will depend on the condition being treated and the individual’s response to the medication. It may be prescribed for short-term relief of allergy symptoms or as a part of a longer treatment plan for other conditions.


Periactin has been shown to be effective in relieving allergy symptoms, including sneezing, itching, watery eyes, and runny nose. It is also used as an appetite stimulant in certain situations, such as in individuals with poor appetite or weight loss.


Periactin may interact with other medications, including sedatives, tranquilizers, and monoamine oxidase inhibitors (MAOIs). It is important to inform your healthcare provider about all medications you are taking to avoid potential interactions.

Consultation with a Healthcare Professional

Periactin is a prescription medication, and it is important to consult with a healthcare professional to determine if it is appropriate for your specific situation. They will consider factors such as your medical history, existing conditions, and other medications you may be taking before prescribing Periactin.

WARNING: This briefing provides general information about Periactin (cyproheptadine) and is not a substitute for professional medical advice. It is essential to consult with a healthcare professional for personalized advice and to address any specific concerns you may have about Periactin or its usage.