Probalan is a brand name for the medication probenecid. Here is a briefing about Probalan (probenecid):

Drug Classification

Probalan is classified as a uricosuric agent and a medication used in the treatment of gout.


Probalan is primarily used to treat gout, a type of arthritis caused by the buildup of uric acid crystals in the joints. It is prescribed as an adjunctive therapy to help lower uric acid levels in the blood and prevent gout attacks.

Mechanism of Action

Probalan works by inhibiting the reabsorption of uric acid in the kidneys, thereby increasing its excretion from the body. This helps to reduce the concentration of uric acid in the blood and prevent the formation of urate crystals in the joints.


Probalan is usually taken orally, with or without food. The dosage and duration of treatment will depend on various factors, such as the severity of gout, the individual’s response to the medication, and other medical considerations. It is important to follow the prescribed instructions carefully.

Precautions and Contraindications

Probalan should be used with caution in individuals with certain medical conditions, such as kidney disease, peptic ulcers, or blood disorders. It may also interact with other medications, such as antibiotics or anticoagulants. It is important to inform your healthcare provider about any existing medical conditions or medications you are taking.

Side Effects

Common side effects of Probalan may include gastrointestinal symptoms such as stomach upset, nausea, vomiting, or diarrhea. It may also cause an increase in uric acid levels initially, which can lead to gout attacks. If you experience severe or persistent side effects, it is important to contact your healthcare provider.

Duration of Treatment

The duration of Probalan treatment will depend on the individual’s response to the medication and the specific goals of therapy. It is usually prescribed for long-term use to help manage and prevent gout attacks.


Probalan has been shown to be effective in reducing uric acid levels and preventing gout attacks when used as part of a comprehensive treatment plan that includes lifestyle modifications and other medications as necessary.


Probalan may interact with other medications, including certain antibiotics, oral anticoagulants, and medications that affect renal function. It is important to inform your healthcare provider about all medications you are taking to avoid potential interactions.

Consultation with a Healthcare Professional

Probalan is a prescription medication, and it is important to consult with a healthcare professional to determine if it is appropriate for your specific situation. They will consider factors such as your medical history, existing conditions, and other medications you may be taking before prescribing Probalan.

WARNING: This briefing provides general information about Probalan (probenecid) and is not a substitute for professional medical advice. It is essential to consult with a healthcare professional for personalized advice and to address any specific concerns you may have about Probalan or its usage.